Monday, January 26, 2009

Herbal

Anthropology of herbalism

Further information: Zoopharmacognosy

People on all continents have used hundreds to thousands of indigenous plants for treatment of ailments since prehistoric times.The first generally accepted use of plants as healing agents was depicted in the cave paintings discovered in the Lascaux caves in France, which have been radiocarbon-dated to between 13,000-25,000 BC. Medicinal herbs were found in the personal effects of an Ice man, whose body was frozen in the Swiss Alps for more than 5,300 years, which appear to have been used to treat the parasites found in his intestines. Anthropology or Anthropologists theorize that animals evolved a tendency to seek out bitter plant parts in response to illness.


Indigenous healers often claim to have learned by observing that sick animals change their food preferences to nibble at bitter herbs they would normally reject.[4] Field biologists have provided corroborating evidence based on observation of diverse species, such as chimpanzees, chickens, sheep and butterflies. Lowland gorillas take 90% of their diet from the fruits of Aframomum melegueta, a relative of the ginger plant, that is a potent antimicrobial and apparently keeps shigellosis and similar infections at bay.[5]

Researchers from Ohio Wesleyan University found that some birds select nesting material rich in antimicrobial agents which protect their young from harmful bacteria.[6]

Sick animals tend to forage plants rich in secondary metabolites, such as tannins and alkaloids.[7] Since these phytochemicals often have antiviral, antibacterial, antifungal and antihelminthic properties, a plausible case can be made for self-medication by animals in the wild.[5]

Some animals have digestive systems especially adapted to cope with certain plant toxins. For example, the koala can live on the leaves and shoots of the eucalyptus, a plant that is dangerous to most animals.[8]A plant that is harmless to a particular animal may not be safe for humans to ingest.[9] A reasonable conjecture is that these discoveries were traditionally collected by the medicine people of indigenous tribes, who then passed on safety information and cautions.

The use of herbs and spices in cuisine developed in part as a response to the threat of food-born pathogens. Studies show that in tropical climates where pathogens are the most abundant recipes are the most highly spiced. Further, the spices with the most potent antimicrobial activity tend to be selected.[10]In all cultures vegetables are spiced less than meat, presumably because they are more resistant to spoilage.[11]

[edit] Herbs in history
Borage from Project Gutenberg EBook of Culinary Herbs: Their Cultivation Harvesting Curing and Uses, by M. G. Kains

In the written record, the study of herbs dates back over 5,000 years to the Sumerians, who described well-established medicinal uses for such plants as laurel, caraway, and thyme. Ancient Egyptian medicine of 1000 B.C. are known to have used garlic, opium, castor oil, coriander, mint, indigo, and other herbs for medicine and the Old Testament also mentions herb use and cultivation, including mandrake, vetch, caraway, wheat, barley, and rye.

Indian Ayurveda medicine has been using herbs such as turmeric and curcumin possibly as early as 1900 B.C.[12] Many other herbs and minerals used in Ayurveda were later described by ancient Indian herbalists such as Charaka and Sushruta during the 1st millenium BC. The Sushruta Samhita attributed to Sushruta in the 6th century BC describes 700 medicinal plants, 64 preparations from mineral sources, and 57 preparations based on animal sources.[13]

The first Chinese herbal book, the Shennong Bencao Jing, compiled during the Han Dynasty but dating back to a much earlier date, possibly 2700 B.C., lists 365 medicinal plants and their uses - including ma-Huang, the shrub that introduced the drug ephedrine to modern medicine. Succeeding generations augmented on the Shennong Bencao Jing, as in the Yaoxing Lun (Treatise on the Nature of Medicinal Herbs), a 7th century Tang Dynasty treatise on herbal medicine.

The ancient Greeks and Romans made medicinal use of plants. Greek and Roman medicinal practices, as preserved in the writings of Hippocrates and - especially - Galen, provided the patterns for later western medicine. Hippocrates advocated the use of a few simple herbal drugs - along with fresh air, rest, and proper diet. Galen, on the other had, recommended large doses of drug mixtures - including plant, animal, and mineral ingredients. The Greek physician compiled the first European treatise on the properties and uses of medicinal plants, De Materia Medica. In the first century AD, Dioscorides wrote a compendium of more than 500 plants that remained an authoritative reference into the 17th century. Similarly important for herbalists and botanists of later centuries was the Greek book that founded the science of botany, Theophrastus’ Historia Plantarum, written in the fourth century B.C.
Thyme from Project Gutenberg EBook of Culinary Herbs: Their Cultivation Harvesting Curing and Uses, by M. G. Kains

[edit] Middle Ages

The uses of plants for medicine and other purposes changed little in early medieval Europe. Many Greek and Roman writings on medicine, as on other subjects, were preserved by hand copying of manuscripts in monasteries. The monasteries thus tended to become local centers of medical knowledge, and their herb gardens provided the raw materials for simple treatment of common disorders. At the same time, folk medicine in the home and village continues uninterrupted, supporting numerous wandering and settled herbalists. Among these were the “wise-women,” who prescribed herbal remedies often along with spells and enchantments. It was not until the late Middle Ages that women who were knowledgeable in herb lore became the targets of the witch hysteria. One of the most famous women in the herbal tradition was Hildegard of Bingen. A twelfth century Benedictine nun, she wrote a medical text called Causes and Cures.

Medical schools known as Bimaristan began to appear from the 9th century in the medieval Islamic world, which was generally more advanced than medieval Europe at the time. The Arabs venerated Greco-Roman culture and learning, and translated tens of thousands of texts into Arabic for further study.[14] As a trading culture, the Arab travellers had access to plant material from distant places such as China and India. Herbals, medical texts and translations of the classics of antiquity filtered in from east and west.[15] Muslim botanists and Muslim physicians significantly expanded on the earlier knowledge of materia medica. For example, al-Dinawari described more than 637 plant drugs in the 9th century,[16] and Ibn al-Baitar described more than 1,400 different plants, foods and drugs, over 300 of which were his own original discoveries, in the 13th century.[17] The experimental scientific method was introduced into the field of materia medica in the 13th century by the Andalusian-Arab botanist Abu al-Abbas al-Nabati, the teacher of Ibn al-Baitar. Al-Nabati introduced empirical techniques in the testing, description and identification of numerous materia medica, and he separated unverified reports from those supported by actual tests and observations. This allowed the study of materia medica to evolve into the science of pharmacology.[18]

Avicenna's The Canon of Medicine (1025) is considered the first pharmacopoeia,[19][20] and lists 800 tested drugs, plants and minerals.[21] Book Two is devoted to a discussion of the healing properties of herbs, including nutmeg, senna, sandalwood, rhubarb, myrrh, cinammon, and rosewater.[14] Baghdad was an important center for Arab herbalism, as was Al-Andalus between 800 and 1400. Abulcasis (936-1013) of Cordoba authored The Book of Simples, an important source for later European herbals, while Ibn al-Baitar (1197-1248) of Malaga authored the Corpus of Simples, the most complete Arab herbal which introduced 200 new healing herbs, including tamarind, aconite, and nux vomica.[14][22] Other pharmacopoeia books include that written by Abu-Rayhan Biruni in the 11th century[23] and Ibn Zuhr (Avenzoar) in the 12th century (and printed in 1491),[24] The origins of clinical pharmacology also date back to the Middle Ages in Avicenna's The Canon of Medicine, Peter of Spain's Commentary on Isaac, and John of St Amand's Commentary on the Antedotary of Nicholas.[25] In particular, the Canon introduced clinical trials,[26] randomized controlled trials,[27][28] and efficacy tests.[29][30]

Alongside the university system, folk medicine continued to thrive. The continuing importance of herbs for the centuries following the Middle Ages is indicated by the hundreds of herbals published after the invention of printing in the fifteenth century. Theophrastus’ Historia Plantarum was one of the first books to be printed, but Dioscorides’ De Materia Medica, Avicenna's Canon of Medicine and Avenzoar's pharmacopoeia were not far behind.
Marjoram from Project Gutenberg EBook of Culinary Herbs: Their Cultivation Harvesting Curing and Uses, by M. G. Kains

[edit] Modern era

The fifteenth, sixteenth, and seventeenth centuries were the great age of herbals, many of them available for the first time in English and other languages rather than Latin or Greek. The first herbal to be published in English was the anonymous Grete Herball of 1526. The two best-known herbals in English were The Herball or General History of Plants (1597) by John Gerard and The English Physician Enlarged (1653) by Nicholas Culpeper. Gerard’s text was basically a pirated translation of a book by the Belgian herbalist Dodoens and his illustrations came from a German botanical work. The original edition contained many errors due to faulty matching of the two parts. Culpeper’s blend of traditional medicine with astrology, magic, and folklore was ridiculed by the physicians of his day yet his book - like Gerard’s and other herbals - enjoyed phenomenal popularity. The Age of Exploration and the Columbian Exchange introduced new medicinal plants to Europe. The Badianus Manuscript was an illustrated Aztec herbal translated into Latin in the 16th century.

The second millennium, however, also saw the beginning of a slow erosion of the pre-eminent position held by plants as sources of therapeutic effects. This began with the introduction of the physician, the introduction of active chemical drugs (like arsenic, copper sulfate, iron, mercury, and sulfur), followed by the rapid development of chemistry and the other physical sciences, led increasingly to the dominance of chemotherapy - chemical medicine - as the orthodox system of the twentieth century.

[edit] Role of herbal medicine in modern human society
Botánicas, such as this one in Jamaica Plain, Massachusetts, cater to the Latino community and sell herbal cures and folk medicine alongside statues of saints, candles decorated with prayers, lucky bamboo, and other items.

The use of herbs to treat disease is almost universal among non-industrialized societies.[31] A number of traditions came to dominate the practice of herbal medicine at the end of the twentieth century:

* The herbal medicine system, based on Greek and Roman sources
* The Siddha and Ayurvedic medicine systems from India
* Chinese herbal medicine (Chinese herbology)
* Unani-Tibb medicine
* Shamanic Herbalism

Many of the pharmaceuticals currently available to physicians have a long history of use as herbal remedies, including opium, aspirin, digitalis, and quinine. The World Health Organization (WHO) estimates that 80 percent of the world's population presently uses herbal medicine for some aspect of primary health care.[32] Pharmaceuticals are prohibitively expensive for most of the world's population, half of which lives on less than $2 U.S. per day.[33][34][35][36] In comparison, herbal medicines can be grown from seed or gathered from nature for little or no cost. Herbal medicine is a major component in all traditional medicine systems, and a common element in Siddha, Ayurvedic, homeopathic, naturopathic, traditional Chinese medicine, and Native American medicine.

The use of, and search for, drugs and dietary supplements derived from plants have accelerated in recent years. Pharmacologists, microbiologists, botanists, and natural-products chemists are combing the Earth for phytochemicals and leads that could be developed for treatment of various diseases. In fact, according to the World Health Organisation, approximately 25% of modern drugs used in the United States have been derived from plants.[37]

* Three quarters of plants that provide active ingredients for prescription drugs came to the attention of researchers because of their use in traditional medicine.[38][verification needed]
* Among the 120 active compounds currently isolated from the higher plants and widely used in modern medicine today, 80 percent show a positive correlation between their modern therapeutic use and the traditional use of the plants from which they are derived.[39]
* More than two thirds of the world's plant species - at least 35,000 of which are estimated to have medicinal value - come from the developing countries.[verification needed]
* At least 7,000 medical compounds in the modern pharmacopoeia are derived from plants[40]



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